Overview

Speakers

Programme

Sponsors

Registration/Abstracts

Location/Travel

Accommodation

Organisers/Contact

Programme

Download the Programme and Abstracts book for the conference via the link below

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The conference will start around midday on Monday the 10^th of June and finish at lunch time on Thursday the 13^th of June 2024.

Topics of the sessions at the conference are:

• Macromolecular interactions, kinetics and dynamics
• Emerging approaches in biophysics – co-organised by the Association of Resources for Biophysical Research in Europe, ARBRE
• Integrative structural biology – organised by Instruct Eric
• Computational biophysics and artificial intelligence applications
• Molecular bioimaging – organised by the Slovenian Biophysical Society
• Macromolecular design, stability and quality control

Monday 10^th June 2024

13:00	Registration, welcome coffee
14:00	Welcome address
14:15	Synthetic biology for the design of modular protein assemblies and mammalian cell regulation Roman Jerala, National Institute of Chemistry, SI Chair: Gregor Anderluh	Opening plenary
	Session 1: Macromolecular design, stability and quality control Chairs: Gregor Anderluh, Javier Sancho
15:00	Unveiling the molecular biophysics of the oncoprotein MYC and its interactions Maria Sunnerhagen, Linköping University, SE	Invited presentation
15:25	Characterization of new Dps-based protein structures by SRCD Raquel Pacheco, NOVA School of Science and Technology, PT	TNA Beneficiary
15:40	Understanding macromolecular structural features in solution by combining size exclusion chromatography, multi array detectors and integrated analysis Bertrand Raynal, Institut Pasteur, FR	Oral presentation
15:55	Coffee break
16:25	High-throughput light scattering as a powerful tool for molecular characterization, interactions, and quality control Malgorzata Łopaciuk, Waters, Wyatt Technology, DE	Company presentation
16:35	Advancing biomolecular interaction analysis with GatorBio biolayer interferometry technology Jeroen Schoorl, I&L Biosystems, DE	Company presentation
16:45	Novel strategy for mAb developability assessment: focus on the Fab with vibrational spectroscopy Karim Ben Ali Gacem, I2BC CEA Saclay, FR	TNA Beneficiary
17:00	Tracking the steps of a completely de novo designed random protein walker Ajasja Ljubetič, National Institute of Chemistry, SI	Oral presentation
17:15	Poly-affibodies and their binding to membrane receptors: synthesis and biophysical characterization Josef Hamacek, CNRS, FR	Oral presentation
17:30	Design of nanoreactors for plastic depolymerization based on pore-forming toxins Sara García-Linares, Complutense University of Madrid, ES	Invited presentation
17:55	Poster / networking session and welcome reception (Glass Hall)

Tuesday 11^th June 2024

08:00	Welcome coffee
08:30	Live Paint – a versatile new method for super-resolution imaging in live cells Lynne Regan, University of Edinburgh, UK Chair: Iztok Urbančič	Plenary
	Session 2: Macromolecular interactions, kinetics and dynamics Chairs: Maria Sunnerhagen, Serena Rinaldo
09:15	The ABC of oligomannose-6 binding to FimH E. coli adhesin Julie Bouckaert, UGSF, UMR 8576 CNRS and University of Lille, FR	Oral presentation
09:30	NLPs from fungi Moniliopthora perniciosa and oomycete Pythium aphanidermatum display pore-forming activity on GIPC-rich membranes Nika Žibrat, National Institute of Chemistry, SI	Oral presentation
09:45	Exploring the role of the N-terminal tails dynamics of a Dps protein nanocage on plasmid DNA binding Ana J. Carvalho, NOVA School of Science and Technology, PT	TNA Beneficiary
10:00	Coffee break
10:30	A combined microscale thermophoresis and capillary electrophoresis to study protein/small inhibitor interactions directly in cell lysates and in whole cells Solweig Chartier, CNRS, FR	Oral presentation
10:45	Comprehensive characterization of molecular interactions from small molecules to cells using switchSENSE® and RT-IC Stéphane Pinhal, Dynamic Biosensors, DE	Company presentation
10:55	Kinetic mechanism and deteminants of EF-P recruitment to translating ribosomes Vitalii Mudryi, Max Planck Institute for Multidisciplinary Sciences, DE	Invited presentation
11:20	Impact of redox alterations on IDO1 inhibitors binding properties Elisa Bianconi, University of Perugia, IT	Oral presentation
11:35	Biochemical and biophysical characterization of Mycobacterium tuberculosis SseA, a thiosulfate:cyanide sulfurtransferase and its interaction network Salvatore Adinolfi, University of Torino, IT	TNA Beneficiary
11:50	Monolith X: a tool for molecular-scale biophysical measurements Quentin Canelle, Nanotemper Technologies, DE	Company presentation
12:00	Folding of multi-domain proteins – folding intermediates, hidden kinetic traps and cryptic functional features Stefano Gianni, Sapienza University of Rome, IT	Invited presentation
12:25	Lunch
	Session 3: Computational biophysics and artificial intelligence applications Chairs: Jan Dohnalek, Jan Stransky
14:00	Computational biophysics meets medicine – from biomolecular simulations to animal models Laura Orellana, Karolinska Institutet, SE	Invited presentation
14:25	Annotation and validation of nucleic acid structures: increasing the quality and interoperability of the data Bohdan Schneider, Institute of Biotechnology of the Czech Academy of Sciences, Czech Republic	Invited presentation
14:50	Accurate and efficient SAXS/SANS implementation including solvation layer effects suitable for molecular simulations Federico Ballabio, Universitá di Milano, IT	TNA Beneficiary
15:05	Probing protein-induced local membrane deformation: a small-angle scattering and computational study Enrico Federico Semeraro, University of Graz, AT	Oral presentation
15:20	Coffee break
15:50	Identification of ClpC1 inhibitors using an in silico approach Hugo Fraga, FMUP/I3S, PT	TNA Beneficiary
16:05	Orange and Quasar: interactive data exploration for spectroscopy Marko Toplak, University of Ljubljana, SI	Oral presentation
16:20	Molecular Biophysics Database of raw data – MBDB Jan Dohnálek, Institute of Biotechnology of the Czech Academy of Sciences, CZ	Oral Presentation
16:35	Computational tools to get the most out of biophysical data Juan Sabín, AFFINImeter, ES	Invited presentation
17:00	Poster / networking session (until 19:00 in the Glass Hall)
	17:30 ARBRE Assembly until 19:00. Open to all. (The Banquet Room, ground floor)

A guided tour of Ljubljana Botanical Gardens has been arranged to take place at 19:00 on Tuesday 11^th of June. Click here to read more and to sign up.

Wednesday 12^th June 2024

08:00	Welcome coffee
08:30	Instruct-ERIC- pan-European research infrastructure for structural biology. Examples for integrated structural biology studies Harald Schwalbe, Goethe-University, DE Chair: Kristina Djinovic Carugo	Plenary
	Session 4: Integrative structural biology Chairs: Kristina Djinovic Carugo, Marjetka Podobnik
09:15	Intrinsically disordered proteins studied by NMR spectroscopy: insights from 13C direct detection Isabella Felli, University of Florence, IT	Invited presentation
09:40	Progress in the integrative analysis of the pyruvate dehydrogenase complex metabolon Toni Träger, Martin-Luther-University Halle-Wittenberg, DE	TNA Beneficiary
09:55	Spectroscopic insights into the mechanism of hydrazine synthase Wouter Versantvoort, Heinrich-Heine-Universität Düsseldorf, DE	TNA Beneficiary
10:10	Orthogonal spectroscopy-systems for the analysis of protein stability and structural changes Markus Epe, Applied Photophysics, UK	Company presentation
10:20	Coffee break
10:50	Deciphering the intricate hierarchy: subtleties in clathrin heavy chain binding boxes provide selectivity among adaptor proteins of budding yeast Maria Garcia Alai, EMBL, DE	Invited presentation
11:15	A closer look at interactions between actinoporins and lipids: insights through Cryo-EM and molecular dynamics simulations Gašper Šolinc, National institute of Chemistry, SI	Oral presentation
11:30	Integrative structural biology to decipher the mechanism of host cell intoxication by the CyaA toxin Alexandre Chenal, Pasteur Institute, FR	Oral presentation
11:45	Integrative structural biology on cytokine-receptor assemblies for fundamental and translational science Savvas Savvides, Ghent University, BE	Oral presentation
12:00	Pushing the boundaries of cryo-EM throughput and resolution at 200kV Itziar Serna Martin, ThermoFisher, NL	Company presentation
12:10	Cryo-STEM tomography: a bridge between molecular and cellular morphologies Sharon Wolf, Weizmann Institute of Science, IL	Invited presentation
12:35	Lunch
	Session 5: Molecular bioimaging Chairs: Iztok Urbančič, Eva Sevcsik
14:00	Small variations in protein structure induce selectivity in the aggregation process of insulin. Claudio Canale, University of Genoa, IT	Invited presentation
14:25	Alterations in unfolding of FRET-labelled fibronectin in the extracellular matrix of NIH/3T3 fibroblasts and MDA-MD-231 breast cancer cells Matthew Walker, University of Glasgow, UK	TNA Beneficiary
14:40	Microscopes and antarctic fish: how developing high-resolution microscopy for 0°C imaging sheds a new life on cold-adapted systems Anne-Pia Marty, University of Cambridge, UK	Oral presentation
14:55	Measuring biophysical properties of cells and nanoscale bioparticles in health and disease Erdinc Sezgin, Karolinska Institutet, SE	Invited presentation
15:20	Spatial requirements for T-cell receptor triggering probed via a DNA origami-based biointerface Eva Sevcsik, Technischen Universität Wien, AT	Invited presentation
15:45	Coffee break
16:15	Current trends and developments of biophysics in Africa and the actions organized by Society of Africa Biophysical Societies (SABS) Philip Amuyunzu Mang’are, Masinde Muliro University of Science and Technology, KE Chair: Juan Sabin	Networking oral presentation
	Session 6: Company presentations Chair: Kristina Eleršič Filipič
16:30	MINFLUX tracking for real-time observation of biological processes at molecular resolution Ulf Matti, Aberrior Instruments, DE	Company presentation
16:40	The Triceratops SPR #64 – tap into a new dimension with next generation multiplexing SPR Cyrill Bruner, Bruker, CH	Company presentation
16:50	Alto & OpenSPR: Nicoya’s label-free solutions for biologics research Dina Niculaes, Nicoya Lifesciences, CA	Company presentation
17:00	BiacoreTM 1 series – Next generation one needle SPR system from Cytiva Florian Koelle, Cytiva Europe, DE	Company presentation
17:10	Recent advances in biomolecular characterization by mass photometry Matthias Langhorst, Refeyn, DE	Company presentation
17:20	Sandoz Slovenia Tamara Cvijić, Lek Farmacevtska družba, SI	Company presentation
17:30	MOSBRI General Assembly The White Hall (where lectures have been taking place). (The Banquet Room, ground floor) Open to all.
19:30	Congress Dinner (The Grand Union Hall, ground floor)

Thursday 13^th June 2024

08:00	Welcome coffee
	Session 7: Emerging approaches in biophysics Chairs: Patrick England, Josef Houser
08:30	Single-molecule nanopore proteomics: from enzyme dynamics to protein sequencing Giovanni Maglia, University of Groningen, NL	Invited presentation
08:55	Preparation of non-covalent self-assembled nanoparticles for nanomedicine Paolo Di Gianvincenzo, CIC biomaGUNE, ES	TNA Beneficiary
09:10	MAGNA™: a novel single molecule approach for the real-time analysis of biomolecular interactions using magnetic force spectroscopy. Pascale Beurdeley, Depixus, FR	Company presentation
09:20	Forces in chaperone-mediated protein unfolding and cell adhesion Matthias Rief, Technische Universität München, DE	Invited presentation
09:45	Infrared nanospectroscopy a new tool in biophysics Jehan Waeytens, Université Libre de Bruxelles, BE	Oral presentation
10:00	Coffee break
10:30	Site-directed spin labelling and electron paramagnetic resonance for the study of the human flavoprotein Cytochrome P450 reductase Maxime Bizet, CNRS, FR	Oral presentation
10:45	Nanoscale dynamics of biomolecular interactions: from viruses to antibiotics Wouter Roos, University of Groningen, NL	Invited presentation
11:10	Ultimate DSC, a new tool for protein characterization Yannice Ricci, Calneos, FR	Company presentation
11:20	First step toward the development of an optical biosensor based on vibrational spectroscopy for the detection of airborne pathogens Tiziana Mancini, University of Rome La Sapienza, IT	Oral presentation
11:35	From integrative structural biology to cell biology Andrej Šali, University of California, San Francisco, USA Chair: Gregor Anderluh	Closing plenary
12:20	Conclusion, awards ceremony

Programme at a glance